Insulin Resistance: Overview

Insulin resistance is the disorder whereby the body’s muscle cells “resist” the insulin in the processing of glucose. This resistance is typically a prominent feature of Type 2 Diabetes, where insulin resistance (mainly in skeletal muscle cells) means that glucose in the blood is not properly processed by the body, leaving blood sugars too high. Surprisingly, this means that diabetics with Type 2 Diabetes often have high levels of insulin in the blood (“hyperinsulinemia”) but the body simply cannot use that insulin to get rid of the sugar in the blood. Not all types of Diabetes have insulin resistance; Type 1 Diabetes is a lack of insulin, and there are also insulin-deficient subtypes of Type 2 Diabetes.

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